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Combining two repurposed drugs as a promising approach for Alzheimer's disease therapy
Alzheimer disease (AD) represents a major medical problem where mono-therapeutic interventions demonstrated only a limited efficacy so far. We explored the possibility of developing a combinational therapy that might prevent the degradation of neuronal and endothelial structures in this disease. We...
Autores principales: | Chumakov, Ilya, Nabirotchkin, Serguei, Cholet, Nathalie, Milet, Aude, Boucard, Aurélie, Toulorge, Damien, Pereira, Yannick, Graudens, Esther, Traoré, Sory, Foucquier, Julie, Guedj, Mickael, Vial, Emmanuel, Callizot, Noëlle, Steinschneider, Rémy, Maurice, Tangui, Bertrand, Viviane, Scart-Grès, Catherine, Hajj, Rodolphe, Cohen, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378993/ https://www.ncbi.nlm.nih.gov/pubmed/25566747 http://dx.doi.org/10.1038/srep07608 |
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