Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model

A mouse model that recapitulates the human Ewing's sarcoma-specific chromosomal translocation was generated utilizing the Cre/loxP-mediated recombination technique. A cross between Ewsr1-loxP and Fli1-loxP mice and expression of ubiquitous Cre recombinase induced a specific translocation betwee...

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Detalles Bibliográficos
Autores principales: Tanaka, Miwa, Yamaguchi, Shuichi, Yamazaki, Yukari, Kinoshita, Hideyuki, Kuwahara, Koichiro, Nakao, Kazuwa, Jay, Patrick Y., Noda, Tetsuo, Nakamura, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379005/
https://www.ncbi.nlm.nih.gov/pubmed/25591392
http://dx.doi.org/10.1038/srep07826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379005/
https://www.ncbi.nlm.nih.gov/pubmed/25591392
http://dx.doi.org/10.1038/srep07826

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