Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells

Peripheral tolerance is crucial for avoiding activation of self-reactive T cells to tissue-restricted antigens. Sterile tissue injury can break peripheral tolerance, but it is unclear how autoreactive T cells get activated in response to self. An example of a sterile injury is myocardial infarction...

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Detalles Bibliográficos
Autores principales: Van der Borght, Katrien, Scott, Charlotte L., Nindl, Veronika, Bouché, Ann, Martens, Liesbet, Sichien, Dorine, Van Moorleghem, Justine, Vanheerswynghels, Manon, De Prijck, Sofie, Saeys, Yvan, Ludewig, Burkhard, Gillebert, Thierry, Guilliams, Martin, Carmeliet, Peter, Lambrecht, Bart N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379012/
https://www.ncbi.nlm.nih.gov/pubmed/28329691
http://dx.doi.org/10.1016/j.celrep.2017.02.079

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