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A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle

The endocrine system dynamically controls tissue differentiation and homeostasis, but has not been studied using dynamic tissue culture paradigms. Here we show that a microfluidic system supports murine ovarian follicles to produce the human 28-day menstrual cycle hormone profile, which controls hum...

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Detalles Bibliográficos
Autores principales: Xiao, Shuo, Coppeta, Jonathan R., Rogers, Hunter B., Isenberg, Brett C., Zhu, Jie, Olalekan, Susan A., McKinnon, Kelly E., Dokic, Danijela, Rashedi, Alexandra S., Haisenleder, Daniel J., Malpani, Saurabh S., Arnold-Murray, Chanel A., Chen, Kuanwei, Jiang, Mingyang, Bai, Lu, Nguyen, Catherine T., Zhang, Jiyang, Laronda, Monica M., Hope, Thomas J., Maniar, Kruti P., Pavone, Mary Ellen, Avram, Michael J., Sefton, Elizabeth C., Getsios, Spiro, Burdette, Joanna E., Kim, J. Julie, Borenstein, Jeffrey T., Woodruff, Teresa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379057/
https://www.ncbi.nlm.nih.gov/pubmed/28350383
http://dx.doi.org/10.1038/ncomms14584

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