Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

HIV-1 envelope glycoprotein (Env) is the sole target for broadly neutralizing antibodies (bnAbs) and the focus for design of an antibody-based HIV vaccine. The Env trimer is covered by ∼90N-linked glycans, which shield the underlying protein from immune surveillance. bNAbs to HIV develop during infe...

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Detalles Bibliográficos
Autores principales: Cao, Liwei, Diedrich, Jolene K., Kulp, Daniel W., Pauthner, Matthias, He, Lin, Park, Sung-Kyu Robin, Sok, Devin, Su, Ching Yao, Delahunty, Claire M., Menis, Sergey, Andrabi, Raiees, Guenaga, Javier, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Yates III, John R., Paulson, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379070/
https://www.ncbi.nlm.nih.gov/pubmed/28348411
http://dx.doi.org/10.1038/ncomms14954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379070/
https://www.ncbi.nlm.nih.gov/pubmed/28348411
http://dx.doi.org/10.1038/ncomms14954

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