Cargando…

Electrophysiological, Morphological, and Ultrastructural Features of the Injured Spinal Cord Tissue after Transplantation of Human Umbilical Cord Blood Mononuclear Cells Genetically Modified with the VEGF and GDNF Genes

In this study, we examined the efficacy of human umbilical cord blood mononuclear cells (hUCB-MCs), genetically modified with the VEGF and GDNF genes using adenoviral vectors, on posttraumatic regeneration after transplantation into the site of spinal cord injury (SCI) in rats. Thirty days after SCI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mukhamedshina, Y. O., Gilazieva, Z. E., Arkhipova, S. S., Galieva, L. R., Garanina, E. E., Shulman, A. A., Yafarova, G. G., Chelyshev, Y. A., Shamsutdinova, N. V., Rizvanov, A. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379091/ https://www.ncbi.nlm.nih.gov/pubmed/28421147 http://dx.doi.org/10.1155/2017/9857918

Ejemplares similares

Influence of Genetically Modified Human Umbilical Cord Blood Mononuclear Cells on the Expression of Schwann Cell Molecular Determinants in Spinal Cord Injury
por: Galieva, L. R., et al.
Publicado: (2018)

Assessment of Glial Scar, Tissue Sparing, Behavioral Recovery and Axonal Regeneration following Acute Transplantation of Genetically Modified Human Umbilical Cord Blood Cells in a Rat Model of Spinal Cord Contusion
por: Mukhamedshina, Yana O., et al.
Publicado: (2016)

Human Umbilical Cord Blood Cell Transplantation in Neuroregenerative Strategies
por: Galieva, Luisa R., et al.
Publicado: (2017)

Application of Autologous Peripheral Blood Mononuclear Cells into the Area of Spinal Cord Injury in a Subacute Period: A Feasibility Study in Pigs
por: Shulman, Iliya, et al.
Publicado: (2021)

Transplantation of Microglia in the Area of Spinal Cord Injury in an Acute Period Increases Tissue Sparing, but Not Functional Recovery
por: Akhmetzyanova, Elvira R., et al.
Publicado: (2018)

Mesenchymal stem cells and the neuronal microenvironment in the area of spinal cord injury
por: Mukhamedshina, Yana O., et al.
Publicado: (2019)

Cellular and Molecular Gradients in the Ventral Horns With Increasing Distance From the Injury Site After Spinal Cord Contusion
por: Kabdesh, Ilyas M., et al.
Publicado: (2022)

Adipose-Derived Mesenchymal Stem Cell Application Combined With Fibrin Matrix Promotes Structural and Functional Recovery Following Spinal Cord Injury in Rats
por: Mukhamedshina, Yana O., et al.
Publicado: (2018)

Induction of Angiogenesis by Genetically Modified Human Umbilical Cord Blood Mononuclear Cells
por: Gatina, Dilara Z., et al.
Publicado: (2023)

Comparative Analysis of Cytokine Profiles in Cerebrospinal Fluid and Blood Serum in Patients with Acute and Subacute Spinal Cord Injury
por: Sabirov, Davran, et al.
Publicado: (2023)

Genetically modified human umbilical cord blood cells as a promising strategy for treatment of spinal cord injury
por: Mukhamedshina, Yana O., et al.
Publicado: (2016)

Systemic and Local Cytokine Profile following Spinal Cord Injury in Rats: A Multiplex Analysis
por: Mukhamedshina, Yana O., et al.
Publicado: (2017)

Blood Serum Cytokines in Patients with Subacute Spinal Cord Injury: A Pilot Study to Search for Biomarkers of Injury Severity
por: Ogurcov, Sergei, et al.
Publicado: (2021)

Severity- and Time-Dependent Activation of Microglia in Spinal Cord Injury
por: Akhmetzyanova, Elvira Ruslanovna, et al.
Publicado: (2023)

Different Approaches to Modulation of Microglia Phenotypes After Spinal Cord Injury
por: Akhmetzyanova, Elvira, et al.
Publicado: (2019)

Therapeutic Potential of Extracellular Vesicles for the Treatment of Nerve Disorders
por: Galieva, Luisa R., et al.
Publicado: (2019)

GDNF Gene Therapy to Repair the Injured Peripheral Nerve
por: Eggers, Ruben, et al.
Publicado: (2020)

A Comparative Study of Mesenchymal Stem Cell-Derived Extracellular Vesicles’ Local and Systemic Dose-Dependent Administration in Rat Spinal Cord Injury
por: Kostennikov, Alexander, et al.
Publicado: (2022)

Genetically Engineered Artificial Microvesicles Carrying Nerve Growth Factor Restrains the Progression of Autoimmune Encephalomyelitis in an Experimental Mouse Model
por: Alatrash, Reem, et al.
Publicado: (2023)

Allogenic Adipose Derived Stem Cells Transplantation Improved Sciatic Nerve Regeneration in Rats: Autologous Nerve Graft Model
por: Masgutov, Ruslan, et al.
Publicado: (2018)

Intrathecal Injection of Autologous Mesenchymal Stem-Cell-Derived Extracellular Vesicles in Spinal Cord Injury: A Feasibility Study in Pigs
por: Shulman, Ilya, et al.
Publicado: (2023)

The Study of Cerebrospinal Fluid microRNAs in Spinal Cord Injury and Neurodegenerative Diseases: Methodological Problems and Possible Solutions
por: Baichurina, Irina, et al.
Publicado: (2021)

A Biosafety Study of Human Umbilical Cord Blood Mononuclear Cells Transduced with Adenoviral Vector Carrying Human Vascular Endothelial Growth Factor cDNA In Vitro
por: Salafutdinov, Ilnur I., et al.
Publicado: (2023)

Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer
por: Tezcan, Gulcin, et al.
Publicado: (2021)

Spinal Cord Electrophysiology
por: Meyer, Allyn, et al.
Publicado: (2010)

Plasticity of the Injured Spinal Cord
por: Guérout, Nicolas
Publicado: (2021)

Mesenchymal Stem Cell Therapy for Spinal Cord Contusion: A Comparative Study on Small and Large Animal Models
por: Mukhamedshina, Yana, et al.
Publicado: (2019)

Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro
por: Chulpanova, Daria S., et al.
Publicado: (2020)

Increasing Severity of Spinal Cord Injury Results in Microglia/Macrophages With Annular-Shaped Morphology and No Change in Expression of CD40 and Tumor Growth Factor-β During the Chronic Post-injury Stage
por: Akhmetzyanova, Elvira Ruslanovna, et al.
Publicado: (2022)

The spinal cord injured patient : comprehensive management
Publicado: (1991)

Tracheostomy in Spinal Cord Injured Patients
por: Ganuza, Javier-Romero, et al.
Publicado: (2011)

Comparative Analysis of Natural and Cytochalasin B-Induced Membrane Vesicles from Tumor Cells and Mesenchymal Stem Cells
por: Gilazieva, Zarema, et al.
Publicado: (2022)

The ultrastructure of spinal cord perivascular spaces: Implications for the circulation of cerebrospinal fluid
por: Lam, Magdalena A., et al.
Publicado: (2017)

RNA-seq of spinal cord from nerve-injured rats after spinal cord stimulation
por: Stephens, Kimberly E, et al.
Publicado: (2018)

Cytochalasin B-Induced Membrane Vesicles from Human Mesenchymal Stem Cells Overexpressing IL2 Are Able to Stimulate CD8(+) T-Killers to Kill Human Triple Negative Breast Cancer Cells
por: Chulpanova, Daria S., et al.
Publicado: (2021)

The effect of increased ambient temperature on thermoregulatory responses in spinal cord injured people
por: Yoda, Tamae, et al.
Publicado: (2015)

Sexual rehabilitation of the spinal-cord-injured patient
Publicado: (1991)

Astrocyte transplantation for repairing the injured spinal cord
por: Zheng, Xiaolong, et al.
Publicado: (2022)

The neurovascular unit in healthy and injured spinal cord
por: Zhou, Rubing, et al.
Publicado: (2023)

Plasticity of the Injured Human Spinal Cord: Insights Revealed by Spinal Cord Functional MRI
por: Cadotte, David W., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_vbg9lbitnlffrki3mbut7ii3te