Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure

Cholesterol is an important regulator of membrane protein function. However, the exact mechanisms involved in this process are still not fully understood. Here we study how the tertiary and quaternary structure of the mitochondrial translocator protein TSPO, which binds cholesterol with nanomolar af...

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Detalles Bibliográficos
Autores principales: Jaipuria, Garima, Leonov, Andrei, Giller, Karin, Vasa, Suresh Kumar, Jaremko, Łukasz, Jaremko, Mariusz, Linser, Rasmus, Becker, Stefan, Zweckstetter, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379104/
https://www.ncbi.nlm.nih.gov/pubmed/28358007
http://dx.doi.org/10.1038/ncomms14893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379104/
https://www.ncbi.nlm.nih.gov/pubmed/28358007
http://dx.doi.org/10.1038/ncomms14893

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