Cargando…

Glycation of paraoxonase 1 by high glucose instigates endoplasmic reticulum stress to induce endothelial dysfunction in vivo

High-density lipoprotein (HDL) modulates low-density lipoprotein and cell membrane oxidation through the action of paraoxonase-1 (PON1). Endoplasmic reticulum (ER) stress has been linked to a wide range of human pathologies including diabetes, obesity, and atherosclerosis. Previous studies have repo...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Wei, Liu, Xiaoli, Feng, Liru, Yang, Hui, Yu, Weiye, Feng, Tiejian, Wang, Shuangxi, Wang, Jun, Liu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379182/
https://www.ncbi.nlm.nih.gov/pubmed/28374834
http://dx.doi.org/10.1038/srep45827