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Glycation of paraoxonase 1 by high glucose instigates endoplasmic reticulum stress to induce endothelial dysfunction in vivo
High-density lipoprotein (HDL) modulates low-density lipoprotein and cell membrane oxidation through the action of paraoxonase-1 (PON1). Endoplasmic reticulum (ER) stress has been linked to a wide range of human pathologies including diabetes, obesity, and atherosclerosis. Previous studies have repo...
Autores principales: | Yu, Wei, Liu, Xiaoli, Feng, Liru, Yang, Hui, Yu, Weiye, Feng, Tiejian, Wang, Shuangxi, Wang, Jun, Liu, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379182/ https://www.ncbi.nlm.nih.gov/pubmed/28374834 http://dx.doi.org/10.1038/srep45827 |
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