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Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model

Neurodegenerative diseases are characterized by the degeneration of specific brain areas associated with accumulation of disease-related protein in extra- or intra-cellular deposits. Their preclinical investigations are mostly based on genetically-engineered animals. Despite their interest, these mo...

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Detalles Bibliográficos
Autores principales: Bourdenx, Mathieu, Dovero, Sandra, Thiolat, Marie-Laure, Bezard, Erwan, Dehay, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379186/
https://www.ncbi.nlm.nih.gov/pubmed/28374864
http://dx.doi.org/10.1038/srep45831