Fibroblast growth factor 21, assisted by elevated glucose, activates paraventricular nucleus NUCB2/Nesfatin-1 neurons to produce satiety under fed states

Fibroblast growth factor 21 (FGF21), liver-derived hormone, exerts diverse metabolic effects, being considered for clinical application to treat obesity and diabetes. However, its anorexigenic effect is debatable and whether it involves the central mechanism remains unclarified. Moreover, the neuron...

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Detalles Bibliográficos
Autores principales: Santoso, Putra, Nakata, Masanori, Shiizaki, Kazuhiro, Boyang, Zhang, Parmila, Kumari, Otgon-Uul, Zesemdorj, Hashimoto, Koshi, Satoh, Tetsurou, Mori, Masatomo, Kuro-o, Makoto, Yada, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379189/
https://www.ncbi.nlm.nih.gov/pubmed/28374855
http://dx.doi.org/10.1038/srep45819

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