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Postnatal Transitional Weight Loss and Adverse Outcomes in Extremely Premature Neonates

The early postnatal weight loss (EPWL) is highly variable in the extremely low birth weight infants (birth weight <1000 g, ELBW). It is reported to be unassociated with adverse outcomes within a range of 3-21% of birth weight. Its wide range might have contributed to this lack of association. The...

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Detalles Bibliográficos
Autores principales: Verma, Rita P., Shibli, Syed, Komaroff, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379222/
https://www.ncbi.nlm.nih.gov/pubmed/28435650
http://dx.doi.org/10.4081/pr.2017.6962
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author Verma, Rita P.
Shibli, Syed
Komaroff, Eugene
author_facet Verma, Rita P.
Shibli, Syed
Komaroff, Eugene
author_sort Verma, Rita P.
collection PubMed
description The early postnatal weight loss (EPWL) is highly variable in the extremely low birth weight infants (birth weight <1000 g, ELBW). It is reported to be unassociated with adverse outcomes within a range of 3-21% of birth weight. Its wide range might have contributed to this lack of association. The aim of our paper is to study the effects of maximum EPWL, graded as low, medium and large on clinical outcomes in ELBW infants. In a retrospective cohort observational study EPWL was measured as maximum weight loss from birth weight (MWL) in ELBW infants and grouped as low (5-12%) moderate (18.1-12%) and high (18-25%). The clinical course and complications of infants were compared between the groups. Gestational age (GA) was highest and surfactant administration, peak inspiratory pressure requirement, fluid intake, urinary output, oxygen dependent days and the number of oxygen dependent infants at age 28 days were lower in the low MWL compared to the high MWL group. However, all these significant P-values declined after controlling for GA. Diabetes mellitus and pregnancy associated hypertension were not noted in mothers in high MWL group, whereas 38% of mothers in low MWL group suffered from the latter (P=0.05). Maximum postnatal transitional weight loss, assessed in the range of low, moderate and high, is not associated with adverse outcomes independent of gestational age in ELBW infants. Maternal hypertension decreases EPWL in them.
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spelling pubmed-53792222017-04-21 Postnatal Transitional Weight Loss and Adverse Outcomes in Extremely Premature Neonates Verma, Rita P. Shibli, Syed Komaroff, Eugene Pediatr Rep Brief Report The early postnatal weight loss (EPWL) is highly variable in the extremely low birth weight infants (birth weight <1000 g, ELBW). It is reported to be unassociated with adverse outcomes within a range of 3-21% of birth weight. Its wide range might have contributed to this lack of association. The aim of our paper is to study the effects of maximum EPWL, graded as low, medium and large on clinical outcomes in ELBW infants. In a retrospective cohort observational study EPWL was measured as maximum weight loss from birth weight (MWL) in ELBW infants and grouped as low (5-12%) moderate (18.1-12%) and high (18-25%). The clinical course and complications of infants were compared between the groups. Gestational age (GA) was highest and surfactant administration, peak inspiratory pressure requirement, fluid intake, urinary output, oxygen dependent days and the number of oxygen dependent infants at age 28 days were lower in the low MWL compared to the high MWL group. However, all these significant P-values declined after controlling for GA. Diabetes mellitus and pregnancy associated hypertension were not noted in mothers in high MWL group, whereas 38% of mothers in low MWL group suffered from the latter (P=0.05). Maximum postnatal transitional weight loss, assessed in the range of low, moderate and high, is not associated with adverse outcomes independent of gestational age in ELBW infants. Maternal hypertension decreases EPWL in them. PAGEPress Publications, Pavia, Italy 2017-03-23 /pmc/articles/PMC5379222/ /pubmed/28435650 http://dx.doi.org/10.4081/pr.2017.6962 Text en ©Copyright R.P Verma et al., 2017 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Verma, Rita P.
Shibli, Syed
Komaroff, Eugene
Postnatal Transitional Weight Loss and Adverse Outcomes in Extremely Premature Neonates
title Postnatal Transitional Weight Loss and Adverse Outcomes in Extremely Premature Neonates
title_full Postnatal Transitional Weight Loss and Adverse Outcomes in Extremely Premature Neonates
title_fullStr Postnatal Transitional Weight Loss and Adverse Outcomes in Extremely Premature Neonates
title_full_unstemmed Postnatal Transitional Weight Loss and Adverse Outcomes in Extremely Premature Neonates
title_short Postnatal Transitional Weight Loss and Adverse Outcomes in Extremely Premature Neonates
title_sort postnatal transitional weight loss and adverse outcomes in extremely premature neonates
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379222/
https://www.ncbi.nlm.nih.gov/pubmed/28435650
http://dx.doi.org/10.4081/pr.2017.6962
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