Efficacy and safety of setipiprant in seasonal allergic rhinitis: results from Phase 2 and Phase 3 randomized, double-blind, placebo- and active-referenced studies

BACKGROUND: Antagonism of chemoattractant receptor-homologous molecule on T-helper type-2 cells (CRTH2), a G-protein coupled receptor for prostaglandin D2, could be beneficial for treating allergic disorders. We present findings on the efficacy and safety/tolerability of a CRTH2 antagonist (setipipr...

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Detalles Bibliográficos
Autores principales: Ratner, Paul, Andrews, Charles P., Hampel, Frank C., Martin, Bruce, Mohar, Dale E., Bourrelly, Denis, Danaietash, Parisa, Mangialaio, Sara, Dingemanse, Jasper, Hmissi, Abdel, van Bavel, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379543/
https://www.ncbi.nlm.nih.gov/pubmed/28392807
http://dx.doi.org/10.1186/s13223-017-0183-z

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