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Inhibition of protein aggregation by zwitterionic polymer-based core-shell nanogels
Protein aggregation is a process by which misfolded proteins polymerizes into aggregates and forms fibrous structures with a β-sheet conformation, known as amyloids. It is an undesired outcome, as it not only causes numerous neurodegenerative diseases, but is also a major deterrent in the developmen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379557/ https://www.ncbi.nlm.nih.gov/pubmed/28374820 http://dx.doi.org/10.1038/srep45777 |