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Inhibition of protein aggregation by zwitterionic polymer-based core-shell nanogels

Protein aggregation is a process by which misfolded proteins polymerizes into aggregates and forms fibrous structures with a β-sheet conformation, known as amyloids. It is an undesired outcome, as it not only causes numerous neurodegenerative diseases, but is also a major deterrent in the developmen...

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Detalles Bibliográficos
Autores principales: Rajan, Robin, Matsumura, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379557/
https://www.ncbi.nlm.nih.gov/pubmed/28374820
http://dx.doi.org/10.1038/srep45777