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Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice

BACKGROUND: Our previous studies demonstrated that post-weaning social isolation (ISO) in mice induces behavior abnormalities such as deficits of sociability- and attention-like behaviors. These deficits can be attenuated by methylphenidate (MPH), a drug used for attention deficit hyperactivity diso...

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Detalles Bibliográficos
Autores principales: Fujiwara, Hironori, Han, Yaoyu, Ebihara, Ken, Awale, Suresh, Araki, Ryota, Yabe, Takeshi, Matsumoto, Kinzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379572/
https://www.ncbi.nlm.nih.gov/pubmed/28376888
http://dx.doi.org/10.1186/s12906-017-1710-7