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Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice
BACKGROUND: Our previous studies demonstrated that post-weaning social isolation (ISO) in mice induces behavior abnormalities such as deficits of sociability- and attention-like behaviors. These deficits can be attenuated by methylphenidate (MPH), a drug used for attention deficit hyperactivity diso...
Autores principales: | Fujiwara, Hironori, Han, Yaoyu, Ebihara, Ken, Awale, Suresh, Araki, Ryota, Yabe, Takeshi, Matsumoto, Kinzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379572/ https://www.ncbi.nlm.nih.gov/pubmed/28376888 http://dx.doi.org/10.1186/s12906-017-1710-7 |
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