Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA) induces various forms of cerebral infarcts and hemorrhages from vascular amyloid-β accumulation, resulting in acceleration of cognitive impairment, which is currently untreatable. Soluble amyloid-β protein likely impairs cerebrovascular integrity as well as cognitiv...

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Detalles Bibliográficos
Autores principales: Saito, Satoshi, Yamamoto, Yumi, Maki, Takakuni, Hattori, Yorito, Ito, Hideki, Mizuno, Katsuhiko, Harada-Shiba, Mariko, Kalaria, Raj N., Fukushima, Masanori, Takahashi, Ryosuke, Ihara, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379578/
https://www.ncbi.nlm.nih.gov/pubmed/28376923
http://dx.doi.org/10.1186/s40478-017-0429-5

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