Cargando…

The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice

Epidermal homeostasis under normal and healing conditions are critical for the physical and functional maintenance of the skin barrier. It requires a proper balance between keratinocyte proliferation and differentiation under genetic and epigenetic regulations. Here we show that mice carrying a hypo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Gang, Ye, Zhisheng, Shi, Cheng, Sun, Ling, Han, Min, Zhuang, Yuan, Xu, Tian, Zhao, Shimin, Wu, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379632/ https://www.ncbi.nlm.nih.gov/pubmed/28374742 http://dx.doi.org/10.1038/srep45401

Ejemplares similares

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity
por: Rogawski, David S., et al.
Publicado: (2021)

Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1α
por: Zhu, Τao, et al.
Publicado: (2016)

Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors
por: Gao, Yuen, et al.
Publicado: (2021)

The ASH1 HOMOLOG 2 (ASHH2) Histone H3 Methyltransferase Is Required for Ovule and Anther Development in Arabidopsis
por: Grini, Paul E., et al.
Publicado: (2009)

Ash2 acts as an ecdysone receptor coactivator by stabilizing the histone methyltransferase Trr
por: Carbonell, Albert, et al.
Publicado: (2013)

Caf1 regulates the histone methyltransferase activity of Ash1 by sensing unmodified histone H3
por: Yoon, Eojin, et al.
Publicado: (2023)

Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation
por: Perugorria, Maria Jesus, et al.
Publicado: (2012)

Fgfr3 Is a Transcriptional Target of Ap2δ and Ash2l-Containing Histone Methyltransferase Complexes
por: Tan, Cheryl C., et al.
Publicado: (2009)

The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice
por: An, J, et al.
Publicado: (2014)

ASH1L histone methyltransferase regulates the handoff between damage recognition factors in global-genome nucleotide excision repair
por: Balbo Pogliano, Chiara, et al.
Publicado: (2017)

Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters
por: Barsoum, Mirna, et al.
Publicado: (2022)

The histone methyltransferase SET8 is required for S-phase progression
por: Jørgensen, Stine, et al.
Publicado: (2007)

Histone H3K36me2-Specific Methyltransferase ASH1L Promotes MLL-AF9-Induced Leukemogenesis
por: Aljazi, Mohammad B., et al.
Publicado: (2021)

Dual Function of Histone H3 Lysine 36 Methyltransferase ASH1 in Regulation of Hox Gene Expression
por: Tanaka, Yujiro, et al.
Publicado: (2011)

Bombyx mori histone methyltransferase BmAsh2 is essential for silkworm piRNA-mediated sex determination
por: Li, Zhiqian, et al.
Publicado: (2018)

Methylation of histone H4 at aspartate 24 by Protein L-isoaspartate O-methyltransferase (PCMT1) links histone modifications with protein homeostasis
por: Biterge, Burcu, et al.
Publicado: (2014)

Histone Methyltransferases as Therapeutic Targets for Kidney Diseases
por: Yu, Chao, et al.
Publicado: (2019)

Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation
por: Long, Xuehui, et al.
Publicado: (2019)

Histone Methyltransferase SETD2 Is Required for Porcine Early Embryonic Development
por: Shao, Weini, et al.
Publicado: (2022)

Circadian clock function does not require the histone methyltransferase MLL3
por: Baxter, Matthew, et al.
Publicado: (2022)

Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex
por: Weirich, Sara, et al.
Publicado: (2017)

Fluid-electrolyte homeostasis requires histone deacetylase function
por: Hyndman, Kelly A., et al.
Publicado: (2020)

Histone methyltransferase PRDM9 is not essential for meiosis in male mice
por: Mihola, Ondrej, et al.
Publicado: (2019)

Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency
por: Nguyen, Kien, et al.
Publicado: (2017)

Context-Dependent Requirement of Euchromatic Histone Methyltransferase Activity during Reprogramming to Pluripotency
por: Vidal, Simon E., et al.
Publicado: (2020)

The role of histone lysine methyltransferase NSD3 in cancer
por: Han, Xu, et al.
Publicado: (2018)

DPY30 acts as an ASH2L-specific stabilizer to stimulate the enzyme activity of MLL family methyltransferases on different substrates
por: Zhao, Lijie, et al.
Publicado: (2022)

The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness
por: Kari, Vijayalakshmi, et al.
Publicado: (2019)

Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis
por: Pang, Bingyu, et al.
Publicado: (2022)

Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice
por: Kanasaki, Megumi, et al.
Publicado: (2017)

Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin
por: Driskell, Iwona, et al.
Publicado: (2012)

Histone methyltransferase SETDB1 is required for prostate cancer cell proliferation, migration and invasion
por: Sun, Yi, et al.
Publicado: (2014)

Histone H3 lysine 4 methyltransferase is required for facultative heterochromatin at specific loci
por: Zhu, Qiaoqiao, et al.
Publicado: (2019)

Attenuation of Histone Methyltransferase KRYPTONITE-mediated transcriptional gene silencing by Geminivirus
por: Sun, Yan-Wei, et al.
Publicado: (2015)

The histone methyltransferase Suv39h regulates 3T3-L1 adipogenesis
por: Jing, Jia, et al.
Publicado: (2020)

Correction: Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

Chemical Probes of Histone Lysine Methyltransferases
por: Kaniskan, H. Ümit, et al.
Publicado: (2014)

Histone methyltransferase and drug resistance in cancers
por: Yang, Cheng, et al.
Publicado: (2020)

Lysine Ethylation by Histone Lysine Methyltransferases
por: Al Temimi, Abbas H. K., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m87pargrftt91hfmt05k6o3fgt