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Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli

BACKGROUND: Polynucleotide phosphorylase (PNPase, encoded by pnp) is generally thought of as an enzyme dedicated to RNA metabolism. The pleiotropic effects of PNPase deficiency is imputed to altered processing and turnover of mRNAs and small RNAs, which in turn leads to aberrant gene expression. How...

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Detalles Bibliográficos
Autores principales: Carzaniga, Thomas, Sbarufatti, Giulia, Briani, Federica, Dehò, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379764/
https://www.ncbi.nlm.nih.gov/pubmed/28376742
http://dx.doi.org/10.1186/s12866-017-0980-z