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Structural analysis of the role of TPX2 in branching microtubule nucleation

The mitotic spindle consists of microtubules (MTs), which are nucleated by the γ-tubulin ring complex (γ-TuRC). How the γ-TuRC gets activated at the right time and location remains elusive. Recently, it was uncovered that MTs nucleate from preexisting MTs within the mitotic spindle, which requires t...

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Detalles Bibliográficos
Autores principales:	Alfaro-Aco, Raymundo, Thawani, Akanksha, Petry, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379942/ https://www.ncbi.nlm.nih.gov/pubmed/28264915 http://dx.doi.org/10.1083/jcb.201607060

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