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Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages

Signal integration between activating Fc receptors and inhibitory signal regulatory protein α (SIRPα) controls macrophage phagocytosis. Here, using dual-color direct stochastic optical reconstruction microscopy, we report that Fcγ receptor I (FcγRI), FcγRII, and SIRPα are not homogeneously distribut...

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Detalles Bibliográficos
Autores principales:	Lopes, Filipa B., Bálint, Štefan, Valvo, Salvatore, Felce, James H., Hessel, Edith M., Dustin, Michael L., Davis, Daniel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379948/ https://www.ncbi.nlm.nih.gov/pubmed/28289091 http://dx.doi.org/10.1083/jcb.201608094

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