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Molecular mechanism of dynein recruitment to kinetochores by the Rod–Zw10–Zwilch complex and Spindly

The molecular motor dynein concentrates at the kinetochore region of mitotic chromosomes in animals to accelerate spindle microtubule capture and to control spindle checkpoint signaling. In this study, we describe the molecular mechanism used by the Rod–Zw10–Zwilch complex and the adaptor Spindly to...

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Detalles Bibliográficos
Autores principales: Gama, José B., Pereira, Cláudia, Simões, Patrícia A., Celestino, Ricardo, Reis, Rita M., Barbosa, Daniel J., Pires, Helena R., Carvalho, Cátia, Amorim, João, Carvalho, Ana X., Cheerambathur, Dhanya K., Gassmann, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379953/
https://www.ncbi.nlm.nih.gov/pubmed/28320824
http://dx.doi.org/10.1083/jcb.201610108