Neurons eat glutamate to stay alive

Neurons are thought to primarily rely on glucose to fuel mitochondrial metabolism. In this issue, Divakaruni et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612067) show that neurons are also happy to use glutamate. When neurons use this neurotransmitter, its concentration drops, thus pro...

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Detalles Bibliográficos
Autores principales: Fendt, Sarah-Maria, Verstreken, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379959/
https://www.ncbi.nlm.nih.gov/pubmed/28298409
http://dx.doi.org/10.1083/jcb.201702003
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author Fendt, Sarah-Maria
Verstreken, Patrik
author_facet Fendt, Sarah-Maria
Verstreken, Patrik
author_sort Fendt, Sarah-Maria
collection PubMed
description Neurons are thought to primarily rely on glucose to fuel mitochondrial metabolism. In this issue, Divakaruni et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612067) show that neurons are also happy to use glutamate. When neurons use this neurotransmitter, its concentration drops, thus protecting against glutamate-induced excitotoxic stress.
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spelling pubmed-53799592017-10-03 Neurons eat glutamate to stay alive Fendt, Sarah-Maria Verstreken, Patrik J Cell Biol Commentary Neurons are thought to primarily rely on glucose to fuel mitochondrial metabolism. In this issue, Divakaruni et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612067) show that neurons are also happy to use glutamate. When neurons use this neurotransmitter, its concentration drops, thus protecting against glutamate-induced excitotoxic stress. The Rockefeller University Press 2017-04-03 /pmc/articles/PMC5379959/ /pubmed/28298409 http://dx.doi.org/10.1083/jcb.201702003 Text en © 2017 Fendt and Verstreken http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Fendt, Sarah-Maria
Verstreken, Patrik
Neurons eat glutamate to stay alive
title Neurons eat glutamate to stay alive
title_full Neurons eat glutamate to stay alive
title_fullStr Neurons eat glutamate to stay alive
title_full_unstemmed Neurons eat glutamate to stay alive
title_short Neurons eat glutamate to stay alive
title_sort neurons eat glutamate to stay alive
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379959/
https://www.ncbi.nlm.nih.gov/pubmed/28298409
http://dx.doi.org/10.1083/jcb.201702003
work_keys_str_mv AT fendtsarahmaria neuronseatglutamatetostayalive
AT verstrekenpatrik neuronseatglutamatetostayalive

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