Cargando…
AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates the EMT program
Basal-like breast cancer (BLBC) is associated with high-grade, distant metastasis and poor prognosis. Elucidating the determinants of aggressiveness in BLBC may facilitate the development of novel interventions for this challenging disease. In this study, we show that aldo-keto reductase 1 member B1...
Autores principales: | Wu, Xuebiao, Li, Xiaoli, Fu, Qiang, Cao, Qianhua, Chen, Xingyu, Wang, Mengjie, Yu, Jie, Long, Jingpei, Yao, Jun, Liu, Huixin, Wang, Danping, Liao, Ruocen, Dong, Chenfang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379972/ https://www.ncbi.nlm.nih.gov/pubmed/28270406 http://dx.doi.org/10.1084/jem.20160903 |
Ejemplares similares
-
ME1 promotes basal-like breast cancer progression and associates with poor prognosis
por: Liao, Ruocen, et al.
Publicado: (2018) -
Nuclear translocation of PLSCR1 activates STAT1 signaling in basal-like breast cancer
por: Huang, Panpan, et al.
Publicado: (2020) -
Loss of ABAT-Mediated GABAergic System Promotes Basal-Like Breast Cancer Progression by Activating Ca(2+)-NFAT1 Axis
por: Chen, Xingyu, et al.
Publicado: (2019) -
HIST1H1B Promotes Basal-Like Breast Cancer Progression by Modulating CSF2 Expression
por: Liao, Ruocen, et al.
Publicado: (2021) -
Inhibition of UGT8 suppresses basal-like breast cancer progression by attenuating sulfatide–αVβ5 axis
por: Cao, Qianhua, et al.
Publicado: (2018)