Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

The phagocyte respiratory burst is crucial for innate immunity. The transfer of electrons to oxygen is mediated by a membrane-bound heterodimer, comprising gp91phox and p22phox subunits. Deficiency of either subunit leads to severe immunodeficiency. We describe Eros (essential for reactive oxygen sp...

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Detalles Bibliográficos
Autores principales: Thomas, David C., Clare, Simon, Sowerby, John M., Pardo, Mercedes, Juss, Jatinder K., Goulding, David A., van der Weyden, Louise, Storisteanu, Daniel, Prakash, Ananth, Espéli, Marion, Flint, Shaun, Lee, James C., Hoenderdos, Kim, Kane, Leanne, Harcourt, Katherine, Mukhopadhyay, Subhankar, Umrania, Yagnesh, Antrobus, Robin, Nathan, James A., Adams, David J., Bateman, Alex, Choudhary, Jyoti S., Lyons, Paul A., Condliffe, Alison M., Chilvers, Edwin R., Dougan, Gordon, Smith, Kenneth G.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379978/
https://www.ncbi.nlm.nih.gov/pubmed/28351984
http://dx.doi.org/10.1084/jem.20161382

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