HIV: Persistence through division

A long-lived latent reservoir for HIV-1 persists in CD4(+) T cells despite antiretroviral therapy and is the major barrier to cure. In this issue of JEM, Hosmane et al. show that T cell proliferation could explain the long-term persistence of this reservoir.

Detalles Bibliográficos
Autores principales: Cohn, Lillian B., Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379988/
https://www.ncbi.nlm.nih.gov/pubmed/28348204
http://dx.doi.org/10.1084/jem.20170463
Descripción
Sumario:A long-lived latent reservoir for HIV-1 persists in CD4(+) T cells despite antiretroviral therapy and is the major barrier to cure. In this issue of JEM, Hosmane et al. show that T cell proliferation could explain the long-term persistence of this reservoir.

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