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HIV: Persistence through division
A long-lived latent reservoir for HIV-1 persists in CD4(+) T cells despite antiretroviral therapy and is the major barrier to cure. In this issue of JEM, Hosmane et al. show that T cell proliferation could explain the long-term persistence of this reservoir.
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379988/ https://www.ncbi.nlm.nih.gov/pubmed/28348204 http://dx.doi.org/10.1084/jem.20170463 |
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author | Cohn, Lillian B. Nussenzweig, Michel C. |
author_facet | Cohn, Lillian B. Nussenzweig, Michel C. |
author_sort | Cohn, Lillian B. |
collection | PubMed |
description | A long-lived latent reservoir for HIV-1 persists in CD4(+) T cells despite antiretroviral therapy and is the major barrier to cure. In this issue of JEM, Hosmane et al. show that T cell proliferation could explain the long-term persistence of this reservoir. |
format | Online Article Text |
id | pubmed-5379988 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-53799882017-10-03 HIV: Persistence through division Cohn, Lillian B. Nussenzweig, Michel C. J Exp Med News A long-lived latent reservoir for HIV-1 persists in CD4(+) T cells despite antiretroviral therapy and is the major barrier to cure. In this issue of JEM, Hosmane et al. show that T cell proliferation could explain the long-term persistence of this reservoir. The Rockefeller University Press 2017-04-03 /pmc/articles/PMC5379988/ /pubmed/28348204 http://dx.doi.org/10.1084/jem.20170463 Text en © 2017 Cohn and Nussenzweig http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | News Cohn, Lillian B. Nussenzweig, Michel C. HIV: Persistence through division |
title | HIV: Persistence through division |
title_full | HIV: Persistence through division |
title_fullStr | HIV: Persistence through division |
title_full_unstemmed | HIV: Persistence through division |
title_short | HIV: Persistence through division |
title_sort | hiv: persistence through division |
topic | News |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379988/ https://www.ncbi.nlm.nih.gov/pubmed/28348204 http://dx.doi.org/10.1084/jem.20170463 |
work_keys_str_mv | AT cohnlillianb hivpersistencethroughdivision AT nussenzweigmichelc hivpersistencethroughdivision |