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Divalent cations and molecular crowding buffers stabilize G-triplex at physiologically relevant temperatures

G-triplexes are non-canonical DNA structures formed by G-rich sequences with three G-tracts. Putative G-triplex-forming sequences are expected to be more prevalent than putative G-quadruplex-forming sequences. However, the research on G-triplexes is rare. In this work, the effects of molecular crowd...

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Detalles Bibliográficos
Autores principales: Jiang, Hong-Xin, Cui, Yunxi, Zhao, Ting, Fu, Hai-Wei, Koirala, Deepak, Punnoose, Jibin Abraham, Kong, De-Ming, Mao, Hanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380134/
https://www.ncbi.nlm.nih.gov/pubmed/25787838
http://dx.doi.org/10.1038/srep09255