FOXO1 couples metabolic activity and growth state in the vascular endothelium

Endothelial cells (ECs) are plastic cells that can switch between growth states with different bioenergetic and biosynthetic requirements(1). Although quiescent in most healthy tissues, ECs divide and migrate rapidly upon proangiogenic stimulation(2,3). Adjusting endothelial metabolism to growth sta...

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Detalles Bibliográficos
Autores principales: Wilhelm, Kerstin, Happel, Katharina, Eelen, Guy, Schoors, Sandra, Oellerich, Mark F., Lim, Radiance, Zimmermann, Barbara, Aspalter, Irene M., Franco, Claudio A., Boettger, Thomas, Braun, Thomas, Fruttiger, Marcus, Rajewsky, Klaus, Keller, Charles, Brüning, Jens C., Gerhardt, Holger, Carmeliet, Peter, Potente, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380221/
https://www.ncbi.nlm.nih.gov/pubmed/26735015
http://dx.doi.org/10.1038/nature16498

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