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Age-related spontaneous lacrimal keratoconjunctivitis is accompanied by dysfunctional T regulatory cells
In both humans and animal models the development of Sjögren syndrome (SS) and non-SS keratoconjunctivitis sicca (KCS) increases with age. Here, we investigated the ocular surface and lacrimal gland phenotype of NOD.B10.H2(b) mice at 7–14, 45–50, and 96–100 weeks. Aged mice develop increased corneal...
Autores principales: | Coursey, Terry G., Bian, Fang, Zaheer, Mahira, Pflugfelder, Stephen C., Volpe, Eugene A., de Paiva, Cintia S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380589/ https://www.ncbi.nlm.nih.gov/pubmed/27706128 http://dx.doi.org/10.1038/mi.2016.83 |
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