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Mucosal and Systemic Immune Responses to Influenza H7N9 Antigen HA1–2 Co-Delivered Intranasally with Flagellin or Polyethyleneimine in Mice and Chickens
Consecutive cases of human infection with H7N9 influenza viruses since 2013 in China have prompted efforts to develop an effective treatment. Subunit vaccines introduced by intranasal administration can block an infection at its primary site; flagellin (fliC) and polyethyleneimine (PEI) have been sh...
Autores principales: | Song, Li, Xiong, Dan, Song, Hongqin, Wu, Lili, Zhang, Meihua, Kang, Xilong, Pan, Zhiming, Jiao, Xinan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380672/ https://www.ncbi.nlm.nih.gov/pubmed/28424686 http://dx.doi.org/10.3389/fimmu.2017.00326 |
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