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Induction of Protective Immunity against Toxoplasma gondii in Mice by Nucleoside Triphosphate Hydrolase-II (NTPase-II) Self-amplifying RNA Vaccine Encapsulated in Lipid Nanoparticle (LNP)

RNA-based vaccine represents an irresistible and safe immunization strategy with decreasing theoretical risks of genomic integration and malignant cell transformation. To our knowledge, however, there is no report about development of RNA vaccine against Toxoplasma gondii infection. We have previous...

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Detalles Bibliográficos
Autores principales: Luo, Fangjun, Zheng, Lina, Hu, Yue, Liu, Shuxian, Wang, Yan, Xiong, Zhongkui, Hu, Xin, Tan, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380742/
https://www.ncbi.nlm.nih.gov/pubmed/28424680
http://dx.doi.org/10.3389/fmicb.2017.00605