The complement system in age-related macular degeneration: A review of rare genetic variants and implications for personalized treatment

Age-related macular degeneration (AMD) is a progressive retinal disease and the major cause of irreversible vision loss in the elderly. Numerous studies have found both common and rare genetic variants in the complement pathway to play a role in the pathogenesis of AMD. In this review we provide an...

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Detalles Bibliográficos
Autores principales: Geerlings, Maartje J., de Jong, Eiko K., den Hollander, Anneke I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380947/
https://www.ncbi.nlm.nih.gov/pubmed/27939104
http://dx.doi.org/10.1016/j.molimm.2016.11.016

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