Genetic and Epigenetic Alterations of TERT Are Associated with Inferior Outcome in Adolescent and Young Adult Patients with Melanoma

Progression of melanoma to distant sites in adolescents and young adults (AYAs) is not reliably predicted by clinicopathologic criteria. TERT promoter mutations when combined with BRAF/NRAS mutations correlate with adverse outcome in adult melanoma. To determine the prognostic value of TERT alterati...

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Detalles Bibliográficos
Autores principales: Seynnaeve, Brittani, Lee, Seungjae, Borah, Sumit, Park, Yongseok, Pappo, Alberto, Kirkwood, John M., Bahrami, Armita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381111/
https://www.ncbi.nlm.nih.gov/pubmed/28378855
http://dx.doi.org/10.1038/srep45704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381111/
https://www.ncbi.nlm.nih.gov/pubmed/28378855
http://dx.doi.org/10.1038/srep45704

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