Increased TET1 Expression in Inflammatory Microenvironment of Hyperinsulinemia Enhances the Response of Endometrial Cancer to Estrogen by Epigenetic Modulation of GPER

Background: Insulin resistance (IR) has been well studied in the initiation and development of endometrial endometrioid carcinoma (EEC). As yet, it has been largely neglected for estrogen sensitivity in local endometrium in hyperinsulinemia-induced systemic microenvironment. The aim of this study wa...

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Detalles Bibliográficos
Autores principales: Lv, Qiao-Ying, Xie, Bing-Ying, Yang, Bing-Yi, Ning, Cheng-Cheng, Shan, Wei-Wei, Gu, Chao, Luo, Xue-Zhen, Chen, Xiao-Jun, Zhang, Zhen-Bo, Feng, You-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381179/
https://www.ncbi.nlm.nih.gov/pubmed/28382153
http://dx.doi.org/10.7150/jca.17064

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