Analysis of origin and protein-protein interaction maps suggests distinct oncogenic role of nuclear EGFR during cancer evolution

Receptor tyrosine kinase EGFR usually is localized on plasma membrane to induce progression of many cancers including cancers in children (Bodey et al. In Vivo. 2005, 19:931-41), but it contains a nuclear localization signal (NLS) that mediates EGFR nuclear translocation (Lin et al. Nat Cell Biol. 2...

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Detalles Bibliográficos
Autores principales: Sharip, Ainur, Abdukhakimova, Diyora, Wang, Xiao, Kim, Alexey, Kim, Yevgeniy, Sharip, Aigul, Orakov, Askarbek, Miao, Lixia, Sun, Qinglei, Chen, Yue, Chen, Zhenbang, Xie, Yingqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381180/
https://www.ncbi.nlm.nih.gov/pubmed/28382154
http://dx.doi.org/10.7150/jca.17961

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