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2′-Epi-uscharin from the Latex of Calotropis gigantea with HIF-1 Inhibitory Activity

Two stereoisomeric cardenolides, uscharin (1) and a new compound, 2′-epi-uscharin (2), were isolated from the latex of Calotropis gigantea (Asclepiadaceae). Their structures were fully elucidated based on their spectroscopic data, X-ray crystallographic data and chemical evidences. Both epimers (1 a...

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Detalles Bibliográficos
Autores principales:	Parhira, Supawadee, Zhu, Guo-Yuan, Jiang, Ren-Wang, Liu, Liang, Bai, Li-Ping, Jiang, Zhi-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381191/ https://www.ncbi.nlm.nih.gov/pubmed/24756103 http://dx.doi.org/10.1038/srep04748

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