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Deployable micro-traps to sequester motile bacteria

The development of strategies to reduce the load of unwanted bacteria is a fundamental challenge in industrial processing, environmental sciences and medical applications. Here, we report a new method to sequester motile bacteria from a liquid, based on passive, deployable micro-traps that confine b...

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Detalles Bibliográficos
Autores principales: Di Giacomo, Raffaele, Krödel, Sebastian, Maresca, Bruno, Benzoni, Patrizia, Rusconi, Roberto, Stocker, Roman, Daraio, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381207/
https://www.ncbi.nlm.nih.gov/pubmed/28378786
http://dx.doi.org/10.1038/srep45897
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author Di Giacomo, Raffaele
Krödel, Sebastian
Maresca, Bruno
Benzoni, Patrizia
Rusconi, Roberto
Stocker, Roman
Daraio, Chiara
author_facet Di Giacomo, Raffaele
Krödel, Sebastian
Maresca, Bruno
Benzoni, Patrizia
Rusconi, Roberto
Stocker, Roman
Daraio, Chiara
author_sort Di Giacomo, Raffaele
collection PubMed
description The development of strategies to reduce the load of unwanted bacteria is a fundamental challenge in industrial processing, environmental sciences and medical applications. Here, we report a new method to sequester motile bacteria from a liquid, based on passive, deployable micro-traps that confine bacteria using micro-funnels that open into trapping chambers. Even in low concentrations, micro-traps afford a 70% reduction in the amount of bacteria in a liquid sample, with a potential to reach >90% as shown by modelling improved geometries. This work introduces a new approach to contain the growth of bacteria without chemical means, an advantage of particular importance given the alarming growth of pan-drug-resistant bacteria.
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spelling pubmed-53812072017-04-10 Deployable micro-traps to sequester motile bacteria Di Giacomo, Raffaele Krödel, Sebastian Maresca, Bruno Benzoni, Patrizia Rusconi, Roberto Stocker, Roman Daraio, Chiara Sci Rep Article The development of strategies to reduce the load of unwanted bacteria is a fundamental challenge in industrial processing, environmental sciences and medical applications. Here, we report a new method to sequester motile bacteria from a liquid, based on passive, deployable micro-traps that confine bacteria using micro-funnels that open into trapping chambers. Even in low concentrations, micro-traps afford a 70% reduction in the amount of bacteria in a liquid sample, with a potential to reach >90% as shown by modelling improved geometries. This work introduces a new approach to contain the growth of bacteria without chemical means, an advantage of particular importance given the alarming growth of pan-drug-resistant bacteria. Nature Publishing Group 2017-04-05 /pmc/articles/PMC5381207/ /pubmed/28378786 http://dx.doi.org/10.1038/srep45897 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Di Giacomo, Raffaele
Krödel, Sebastian
Maresca, Bruno
Benzoni, Patrizia
Rusconi, Roberto
Stocker, Roman
Daraio, Chiara
Deployable micro-traps to sequester motile bacteria
title Deployable micro-traps to sequester motile bacteria
title_full Deployable micro-traps to sequester motile bacteria
title_fullStr Deployable micro-traps to sequester motile bacteria
title_full_unstemmed Deployable micro-traps to sequester motile bacteria
title_short Deployable micro-traps to sequester motile bacteria
title_sort deployable micro-traps to sequester motile bacteria
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381207/
https://www.ncbi.nlm.nih.gov/pubmed/28378786
http://dx.doi.org/10.1038/srep45897
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