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Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Fancd2 is a component of the Fanconi anemia (FA) DNA repair pathway, which is frequently found defective in human cancers. The full repertoire of Fancd2 functions in normal development and tumorigenesis remains to be determined. Here we developed a Flag- and hemagglutinin-tagged Fancd2 knock-in mous...

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Detalles Bibliográficos
Autores principales: Zhang, Tingting, Du, Wei, Wilson, Andrew F., Namekawa, Satoshi H., Andreassen, Paul R., Meetei, Amom Ruhikanta, Pang, Qishen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381226/
https://www.ncbi.nlm.nih.gov/pubmed/28378742
http://dx.doi.org/10.1038/srep45626

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