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Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models

BACKGROUND: The Hedgehog pathway receptor smoothened (SMO) has critical roles in tumor progression. However, whether SMO is a key factor regulating gastric cancer chemotherapy resistance is unknown. MATERIAL/METHODS: We investigated the potential functions of SMO in inducing gastric cancer paclitaxe...

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Detalles Bibliográficos
Autores principales:	Ma, Huifa, Tian, Yongsheng, Yu, Xiangyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381338/ https://www.ncbi.nlm.nih.gov/pubmed/28350784 http://dx.doi.org/10.12659/MSM.903012

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