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Does selection for short sleep duration explain human vulnerability to Alzheimer’s disease?

Compared with other primates, humans sleep less and have a much higher prevalence of Alzheimer ’s disease (AD) pathology. This article reviews evidence relevant to the hypothesis that natural selection for shorter sleep time in humans has compromised the efficacy of physiological mechanisms that pro...

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Detalles Bibliográficos
Autores principales: Nesse, Randolph M, Finch, Caleb E, Nunn, Charles L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381352/
https://www.ncbi.nlm.nih.gov/pubmed/28096295
http://dx.doi.org/10.1093/emph/eow035