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Epigenetic Modification of the Leptin Promoter in Diet-Induced Obese Mice and the Effects of N-3 Polyunsaturated Fatty Acids

We report evidence of a detailed epigenetic modification of the leptin promoter and the effects of n-3 polyunsaturated fatty acids (n-3 PUFAs), which is closely associated with the leptin gene transcription in obesity. In the adipose tissue of diet induced obese (DIO) mice, methylation of the CpG is...

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Detalles Bibliográficos
Autores principales:	Shen, Wenwen, Wang, Cui, Xia, Lulu, Fan, Chaonan, Dong, Hua, Deckelbaum, Richard J., Qi, Kemin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381469/ https://www.ncbi.nlm.nih.gov/pubmed/24923522 http://dx.doi.org/10.1038/srep05282

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