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Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors

Gout/hyperuricemia is a common multifactorial disease having typical environmental risks. Recently, common dysfunctional variants of ABCG2, a urate exporter gene also known as BCRP, are revealed to be a major cause of gout/hyperuricemia. Here, we compared the influence of ABCG2 dysfunction on serum...

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Detalles Bibliográficos
Autores principales:	Nakayama, Akiyoshi, Matsuo, Hirotaka, Nakaoka, Hirofumi, Nakamura, Takahiro, Nakashima, Hiroshi, Takada, Yuzo, Oikawa, Yuji, Takada, Tappei, Sakiyama, Masayuki, Shimizu, Seiko, Kawamura, Yusuke, Chiba, Toshinori, Abe, Junko, Wakai, Kenji, Kawai, Sayo, Okada, Rieko, Tamura, Takashi, Shichijo, Yuka, Akashi, Airi, Suzuki, Hiroshi, Hosoya, Tatsuo, Sakurai, Yutaka, Ichida, Kimiyoshi, Shinomiya, Nariyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381477/ https://www.ncbi.nlm.nih.gov/pubmed/24909660 http://dx.doi.org/10.1038/srep05227

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