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Self in vivo production of a synthetic biological drug CTLA4Ig using a minicircle vector

Cytotoxic T lymphocyte-associated antigen 4 immunoglobulin fusion protein (CTLA4Ig, abatacept) is a B7/CD28 costimulation inhibitor that can ward off the immune response by preventing the activation of naïve T cells. This therapeutic agent is administered to patients with autoimmune diseases such as...

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Detalles Bibliográficos
Autores principales:	Rim, Yeri Alice, Yi, Hyoju, Kim, Youngkyun, Park, Narae, Jung, Hyerin, Kim, Juryun, Jung, Seung Min, Park, Sung-Hwan, Ju, Ji Hyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381501/ https://www.ncbi.nlm.nih.gov/pubmed/25374010 http://dx.doi.org/10.1038/srep06935

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