Aortic Dissection is Associated with Reduced Polycystin-1 Expression, an Abnormality That Leads to Increased ERK Phosphorylation in Vascular Smooth Muscle Cells

The vascular smooth muscle cell (VSMC) phenotypic switch is a key pathophysiological change in various cardiovascular diseases, such as aortic dissection (AD), with a high morbidity. Polycystin-1 (PC1) is significantly downregulated in the VSMCs of AD patients. PC1 is an integral membrane glycoprote...

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Detalles Bibliográficos
Autores principales: Feng, J., Ge, S., Zhang, L., Che, H., Liang, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381529/
https://www.ncbi.nlm.nih.gov/pubmed/28076932
http://dx.doi.org/10.4081/ejh.2016.2711

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