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A preliminary study of the relationship between breast cancer metastasis and loss of heterozygosity by using exome sequencing
We explored the feasibility of studying loss of heterozygosity (LOH) by using exome sequencing and compared the differences in genetic LOH between primary breast tumors and metastatic lesions. Exome sequencing was conducted to investigate the genetic LOH in the peripheral blood, a primary tumor, and...
Autores principales: | Li, Hongsheng, Yang, Bo, Xing, Ke, Yuan, Nangui, Wang, Bo, Chen, Zhenyu, He, Weixing, Zhou, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381542/ https://www.ncbi.nlm.nih.gov/pubmed/24964733 http://dx.doi.org/10.1038/srep05460 |
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