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A preliminary study of the relationship between breast cancer metastasis and loss of heterozygosity by using exome sequencing

We explored the feasibility of studying loss of heterozygosity (LOH) by using exome sequencing and compared the differences in genetic LOH between primary breast tumors and metastatic lesions. Exome sequencing was conducted to investigate the genetic LOH in the peripheral blood, a primary tumor, and...

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Detalles Bibliográficos
Autores principales: Li, Hongsheng, Yang, Bo, Xing, Ke, Yuan, Nangui, Wang, Bo, Chen, Zhenyu, He, Weixing, Zhou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381542/
https://www.ncbi.nlm.nih.gov/pubmed/24964733
http://dx.doi.org/10.1038/srep05460

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