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LXRα and LXRβ Nuclear Receptors Evolved in the Common Ancestor of Gnathostomes

Nuclear receptors (NRs) regulate numerous aspects of the endocrine system. They mediate endogenous and exogenous cues, ensuring a homeostatic control of development and metabolism. Gene duplication, loss and mutation have shaped the repertoire and function of NRs in metazoans. Here, we examine the e...

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Detalles Bibliográficos
Autores principales: Fonseca, Elza, Ruivo, Raquel, Lopes-Marques, Mónica, Zhang, Huixian, Santos, Miguel M., Venkatesh, Byrappa, Castro, L. Filipe C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381633/
https://www.ncbi.nlm.nih.gov/pubmed/28057729
http://dx.doi.org/10.1093/gbe/evw305