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In vivo inhibition of influenza A virus replication by RNA interference targeting the PB2 subunit via intratracheal delivery

BACKGROUND: Influenza virus infection is a major threat to human health. Small interfering RNA (siRNA) is a promising approach for the prevention and treatment of viral infections. In this study, we constructed a series of DNA vector-based short hairpin RNAs (shRNAs) that target various genes of the...

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Detalles Bibliográficos
Autores principales:	Huang, Daniel Tsung-Ning, Lu, Chun-Yi, Shao, Pei-Lan, Chang, Luan-Yin, Wang, Jin-Yuan, Chang, Yi-Hsuan, Lai, Mei-Ju, Chi, Ya-Hui, Huang, Li-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381882/ https://www.ncbi.nlm.nih.gov/pubmed/28380007 http://dx.doi.org/10.1371/journal.pone.0174523

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