Application of JC1 for non-toxic isolation of cells with MDR transporter activity by flow cytometry

The DNA intercalating dye Hoechst 33342 or its close analog DCV are actively removed from cells by the multidrug resistance transporter ABCG2, a protein overexpressed in metastatic cells and somatic stem cells. In bivariate blue-red flow cytometry fluorescent plots active Hoechst or DCV efflux combi...

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Detalles Bibliográficos
Autores principales: Wolosin, J. Mario, Zamudio, Aldo, Wang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381900/
https://www.ncbi.nlm.nih.gov/pubmed/28380010
http://dx.doi.org/10.1371/journal.pone.0174905

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