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Repeated brief isoflurane anesthesia during early postnatal development produces negligible changes on adult behavior in male mice
Brain development is a complex process regulated by genetic programs and activity-dependent neuronal connectivity. Anesthetics profoundly alter neuronal excitability, and anesthesia during early brain development has been consistently associated with neuroapoptosis, altered synaptogenesis, and persi...
Autores principales: | Rosenholm, Marko, Paro, Emmi, Antila, Hanna, Võikar, Vootele, Rantamäki, Tomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381906/ https://www.ncbi.nlm.nih.gov/pubmed/28380075 http://dx.doi.org/10.1371/journal.pone.0175258 |
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